Anti-EDF1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-EDF1/FITC Conjugated抗体

Anti-EDF1/FITC Conjugated抗体

商家询价

产品名称: Anti-EDF1/FITC Conjugated抗体

英文名称: Anti-EDF1/FITC

产品编号: YB--14503R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-EDF1/FITC Conjugated抗体

产品编号 YB-14503R-FITC
英文名称 Anti-EDF1/FITC
中文名称 FITC标记的内皮分化相关因子1抗体
别    名 CAP19; EDF-1; edf1; EDF1_HUMAN; Endothelial differentiation related factor 1; Endothelial differentiation-related factor 1; MBF1; MGC9058; Multiprotein bridging factor 1; Multiprotein-bridging factor 1.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  转录调节因子  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDF1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.

Subcellular Location:
Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.

Tissue Specificity:
Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.

Post-translational modifications:
Phosphorylated (by PKA and PKC).

Similarity:
Contains 1 HTH cro/C1-type DNA-binding domain.

Database links:

Entrez Gene: 8721 Human

Entrez Gene: 417286 Chicken

Entrez Gene: 515380 Cow

Entrez Gene: 59022 Mouse

Entrez Gene: 296570 Rat

Omim: 605107 Human

SwissProt: Q3T0V7 Cow

SwissProt: O60869 Human

SwissProt: Q9JMG1 Mouse

SwissProt: P69736 Rat

Unigene: 174050 Human

Unigene: 29945 Mouse

Unigene: 17092 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications