Cofilin抗体-抗体-抗体-生物在线
Cofilin抗体

Cofilin抗体

商家询价

产品名称: Cofilin抗体

英文名称: CofilinAntibody

产品编号: XY10960-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com

 COFILIN抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Published applications IF, IHC, WB Publications 4 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 10960-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 10960-1-AP(CFL1 antibody) at dilution of 1:1000
  • 10960-1-AP;human cervical cancerImmunohistochemical of paraffin-embedded human cervical cancer using 10960-1-AP(CFL1 antibody) at dilution of 1:50 (under 10x lens)
  • 10960-1-AP;human cervical cancerImmunohistochemical of paraffin-embedded human cervical cancer using 10960-1-AP(CFL1 antibody) at dilution of 1:50 (under 40x lens)
  • 10960-1-AP;NIH/3T3 cellsImmunofluorescent analysis of ( -20℃ Ethanol ) fixed NIH/3T3 cells using 10960-1-AP( Cofilin Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in Mouse brain tissue, human brain tissue, human skin tissue, MCF7 cells, NIH/3T3 cells, rat brain tissue
Positive IHC detected in Human cervical cancer tissue, human heart tissue, human lung cancer tissue
Positive IF detected in NIH/3T3 cells
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200
 COFILIN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Cofilin fusion protein ag1399 Full name Cofilin 1 (non-muscle)
Calculated molecular
weight
18 kDa Observed molecular 
weight
18 kDa
GenBank accession 
number
BC012318 Gene ID (NCBI) 1072
Gene symbol CFL1 Synonyms 18 kDa phosphoprotein, CFL, CFL1, Cofilin 1, cofilin 1 (non muscle), Cofilin, non muscle isoform, p18
Background COFILIN抗体

Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility, cytokinesis, and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation.Phosphorylation at Ser3 can inhibit its activity, also causing translocation from the nucleus to the cytoplasm. COFILIN抗体

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