FANCD2-phospho(S330) 抗体-抗体-抗体-生物在线
FANCD2-phospho(S330) 抗体

FANCD2-phospho(S330) 抗体

商家询价

产品名称： FANCD2-phospho(S330) 抗体

英文名称： FANCD2-phospho(S330) Antibody

产品编号： XY 19543-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 FANCD2-PHOSPHO(S330) 抗体

Applications
Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HL-60 cells
Positive IHC detected in Human testis tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 FANCD2-PHOSPHO(S330) 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 19543-1-AP;HL-60 cellHL-60 cells were subjected to SDS PAGE followed by western blot with 19543-1-AP(FANCD2-phospho antibody) at dilution of 1:200
  • 19543-1-AP;H-testisImmunohistochemical of paraffin-embedded human testis using 19543-1-AP(FANCD2-phospho antibody) at dilution of 1:50 (under 40x lens)
  • 19543-1-AP;H-testisImmunohistochemical of paraffin-embedded human testis using 19543-1-AP(FANCD2-phospho antibody) at dilution of 1:50 (under 10x lens)
Product Information FANCD2-PHOSPHO(S330) 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: Fanconi anemia, complementation group D2
Caculated Molecular
Weight:		 166 kDa Observed Molecular 
Weight:		 150-155kd
GenbankNo NM_033084 GeneID: 2177
Symbol FANCD2 Synonyms DKFZp762A223, FA D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, FLJ23826, Protein FACD2
Background

FANCD2, also named as FACD and FACD2, is required for maintenance of chromosomal stability. FANCD2 promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. It may participate in S phase and G2 phase checkpoint activation upon DNA damage. It promotes BRCA2/FANCD1 loading onto damaged chromatin. FANCD2 may also be involved in B-cell immunoglobulin isotype switching. Defects in FANCD2 are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is to phospho-Ser(330) of FANCD2. FANCD2-PHOSPHO(S330) 抗体

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