FITC标记的基质金属蛋白酶-10抗体
产品名称： FITC标记的基质金属蛋白酶-10抗体
英文名称： Anti-MMP10/FITC
产品编号： HZ-1344R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-MMP10/FITC Conjugated antibody
FITC标记的基质金属蛋白酶-10抗体
| 英文名称 | Anti-MMP10/FITC |
| 中文名称 | FITC标记的基质金属蛋白酶-10抗体 |
| 别 名 | Matrix metalloproteinase 10; Matrix metalloproteinase-10; matrix metalloproteinase 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL2; STMY 2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; StromelysinII; Transin 2; Transin-2; Transin2; stromelysin 2; SL-2; STMY2; MMP 10; AV377895, MMP10. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 心血管 细胞生物 细胞外基质 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MMP10 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Function: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Subcellular Location: Secreted, extracellular space, extracellular matrix (Probable). Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. Database links: Entrez Gene: 4319 Human Entrez Gene: 17384 Mouse Entrez Gene: 117061 Rat Omim: 185260 Human SwissProt: P09238 Human SwissProt: O55123 Mouse SwissProt: P07152 Rat Unigene: 2258 Human Unigene: 14126 Mouse Unigene: 9946 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解（Synthesis and Degradation） MMP10主要用于一些恶性肿瘤，如乳腺癌、胃肠道癌、卵巢癌等与转移浸润的研究 |
蛋白的基质金属蛋白酶（MMP）家族的成员都参与了细胞外基质的击穿在正常生理过程，如生殖、发育和组织的发展，remodeling，以及在疾病过程，如类风湿关节炎和肿瘤转移。分泌的基质金属蛋白酶9的是灭活的，当被激活cleaved-caspase-3 proproteins是细胞外蛋白酶。由这种基因编码的酶degrades proteoglycans和纤维连接蛋白。该基因簇的一部分，基质金属蛋白酶基因定位到染色体11q22.3.